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CEFQUINO-DC

Name: CEFQUINO-DC
Brand: ASTA Pharma
Rating: 5 (19 reviews)

Fourth-generation Cephalosporin
Effective against multiple pathogens

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Ingrediente

Powder vial (20 ml): Contains Cefquinome sulfate 0.675 g.

Diluent vial (15 ml): Each ml contains Benzyl alcohol 10 mg (E1519).

Reconstituted solution (1 ml):

Active ingredient: Cefquinome (as sulfate) 45 mg.
Excipient: Benzyl alcohol (E1519) 10 mg.

Uses

Highly effective for treating respiratory diseases, septicemia caused by E. coli, skin infections, hoof rot, and acute mastitis. Indicated for bacterial infections caused by Cefquinome-sensitive bacteria in horses, cattle, and buffalo.

Propiedades farmacológicas

Pharmacodynamics:

Cefquinome is a bactericidal antibiotic belonging to the fourth-generation cephalosporins with a broad-spectrum activity. It inhibits bacterial growth and division by disrupting bacterial cell wall synthesis. It is highly effective against pathogens causing respiratory diseases in cattle such as Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni; and in pigs such as Actinobacillus pleuropneumoniae, Haemophilus parasuis, and Pasteurella multocida.

Pharmacokinetics:

In cattle: Following subcutaneous administration at 2.5 mg/kg body weight, the maximum concentration (Cmax) is 1 μg/ml, reached in 2 hours (Tmax). Approximately 5% of Cefquinome binds to plasma proteins and is excreted unchanged in urine. In calves, around 90% of the dose is excreted via urine and 5% via feces.

In pigs: Following intramuscular administration at 2.5 mg/kg body weight, Cmax is 0.86–0.88 μg/ml, reached in 1 hour. Cefquinome has a low plasma protein binding (around 14%) and is mainly excreted through urine.

Uso

Inject the diluent into the powder vial, shake well before use. Do not mix with other solvents (e.g., distilled water). Administer intramuscularly or subcutaneously.

Cattle, buffalo, horses, pigs: 1 ml/45 kg body weight (1 mg/kg), once daily (foals: twice daily) for 5–7 consecutive days.
Calves, buffalo calves: 2 ml/45 kg body weight (2 mg/kg), once daily for 3–5 consecutive days.

USE DURING PREGNANCY AND LACTATION:

In cattle, buffalo, and pigs, the medication does not affect reproductive performance (including teratogenicity). However, consult a veterinarian or carefully weigh benefits and risks before use.

OVERDOSE:
At doses of 20 mg/kg body weight in cattle and 3 mg/kg body weight twice daily in foals, the medication remains well tolerated.

WITHDRAWAL PERIOD:

For meat consumption:
For milk extraction:

Contraindicaciones

Do not use in animals with a history of hypersensitivity to cephalosporins or other β-lactam antibiotics.

Efectos secundarios

Subcutaneous injections may cause mild inflammation at the injection site.
Rare cases of hypersensitivity reactions.
Pain may occur at the injection site.

Fecha de caducidad

Product: 24 months.
Reconstituted solution: 10 days at 2–8°C.

Almacenamiento

Store at a temperature not exceeding 30°C. Avoid direct sunlight. Reconstituted solution must be used within 10 days when stored at 2–8°C.

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información adicional

Ingrediente

Powder vial (20 ml): Contains Cefquinome sulfate 0.675 g.

Diluent vial (15 ml): Each ml contains Benzyl alcohol 10 mg (E1519).

Reconstituted solution (1 ml):

Active ingredient: Cefquinome (as sulfate) 45 mg.
Excipient: Benzyl alcohol (E1519) 10 mg.

Uses

Propiedades farmacológicas

Pharmacodynamics:

Pharmacokinetics:

Uso

Inject the diluent into the powder vial, shake well before use. Do not mix with other solvents (e.g., distilled water). Administer intramuscularly or subcutaneously.

Cattle, buffalo, horses, pigs: 1 ml/45 kg body weight (1 mg/kg), once daily (foals: twice daily) for 5–7 consecutive days.
Calves, buffalo calves: 2 ml/45 kg body weight (2 mg/kg), once daily for 3–5 consecutive days.

USE DURING PREGNANCY AND LACTATION:

In cattle, buffalo, and pigs, the medication does not affect reproductive performance (including teratogenicity). However, consult a veterinarian or carefully weigh benefits and risks before use.

OVERDOSE:
At doses of 20 mg/kg body weight in cattle and 3 mg/kg body weight twice daily in foals, the medication remains well tolerated.

WITHDRAWAL PERIOD:

For meat consumption:
For milk extraction:

Contraindicaciones

Do not use in animals with a history of hypersensitivity to cephalosporins or other β-lactam antibiotics.

Efectos secundarios

Subcutaneous injections may cause mild inflammation at the injection site.
Rare cases of hypersensitivity reactions.
Pain may occur at the injection site.

Fecha de caducidad

Product: 24 months.
Reconstituted solution: 10 days at 2–8°C.

Almacenamiento

Store at a temperature not exceeding 30°C. Avoid direct sunlight. Reconstituted solution must be used within 10 days when stored at 2–8°C.

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PRODUCTOS RELACIONADOS

Aa-Vicom

Provides a source of amino acids and vitamins.

ADE Fort

ADE FORT is intended for use as an aid in the prevention and treatment of vitamin A, D and E deficiencies in pigs, sheep and cattle.

Astryl

Treatment of respiratory and digestive tract infections, typhoid in buffalo, cows, pigs and poultry

ATP 3+

Supports energy metabolism for organs like the heart, muscles, liver, and immune cells.

B12 3+

A vital component for cellular activities.

B12-ATP

Anti-fatigue – Health recovery – Stress prevention

Bcom ADE

Treatment for growth disorders, reduced appetite, poor feeding.

Butal-AD

A component of ATP—the energy source for muscle and bone cells.

Calbiron

Treatment for calcium deficiency and anemia.

Calci-B6

For deficiencies in calcium, magnesium, methionine, lysine, and vitamins.

Chymosin

Biological anti-inflammatory preparation.Breaks down casein and fibrin in infectious diseases

Chymosin-XL

Biological anti-inflammatory product

Dexmin

Combination of glucocorticoid and antihistamine

Diclodol

Pain relief - Fever reduction - Anti-inflammatory

Doxy-Sone

Dual Antibiotics – Rapid Absorption – Wide Distribution

Doxysone LA

Dual-action antibiotic with a 48-hour prolonged effect.Fast absorption – wide distribution.

Fe-B12

Fe-B12 - BLOOD TONE - Supplement iron and B12, prevent and treat anemia.

Florcol-LA

Specialized for respiratory and gastrointestinal diseases

Flortyl-LA

Effective against Gram-negative and Gram-positive bacteria

Fluroquin

Antibiotics are widely used in veterinary medicine to treat diseases in cattle, pigs and poultry.

Fosfocin

Treatment of coryza, pasteurellosis,bronchopneumonia, mastitis, genital tract infections.

Loximol

The alleviation of inflammation and pain in both acute and chronic musculo-skeletal disorders.

Marbo-10

Effective against pneumonia and MMA (Mastitis-Metritis-Agalactia).

Mectin

Causes paralysis of worms, immobilizes, and eliminates larvae through the lymphatic system.

Nutrisal

Acts as a reserve energy source (ATP) for muscle and bone cells.

Rimaco FA

Effective against both Gram(-) and Gram (+) bacteria.

Spec-Lin

For the treatment of infections caused by bacteria sensitive to Lincomycin and Spectinomycin.

Tylan-100

Special treatment for asthma, pneumonia, acute and chronic respiratory tract infections.

Vita Bcomplex

Promotes absorption and metabolism in animals, especially animals with metabolic disorders and weak resistance.

ZUTIDYL-LP

Rapid absorption and effective distribution to lung tissues and infection sites.

Zutidyl-XL

Has a special bactericidal effect because the drug reaches high concentrations in plasma.

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