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Fe-B12

Name: Fe-B12
Brand: ASTA Pharma
Rating: 5 (29 reviews)

Fe-B12 - BLOOD TONE - Supplement iron and B12, prevent and treat anemia.

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Ingrediente

Each 1 ml of solution contains:

Iron dextran ................. 100 mg
Vitamin B12 .................. 100 mcg
Solvent q.s. ..................... 1 ml

Uses

Prevention and treatment of anemia in calves, buffalo calves, and piglets.

Propiedades farmacológicas

Iron dextran is a complex of Fe(OH)₃ and dextran with a molecular weight of 5,000–7,500. Iron is essential in treating anemia, and iron deficiency is a major cause of anemia.

After intramuscular injection, the drug is absorbed via the lymphatic system: about 60% of the dose is absorbed within 3 days, and 90% within 1–3 weeks. Most absorption and transport of dextran iron from the injection site to the lymphatic system are handled by macrophages. Some dextran iron may remain around the connective tissues near the injection site and is absorbed slowly over several months.
Once absorbed, dextran iron rapidly enters the bloodstream via the lymphatic system and is gradually taken up by cells in the reticuloendothelial system (liver, spleen, bone marrow). Iron is released from the dextran complex, and dextran is either metabolized or excreted. Iron immediately binds to proteins such as hemosiderin, transferrin, or ferritin. Iron can cross the placenta, though the exact form is unknown. Only a small amount is excreted through milk.
Iron is not completely eliminated from the body. Free iron from hemoglobin breakdown is reused by the body, with only small amounts lost through hair and nail growth, skin shedding, and gastrointestinal mucosal turnover. Iron accumulation can occur with repeated doses, with minimal excretion via feces, bile, or urine.

Vitamin B12 is crucial for DNA synthesis. A deficiency in Vitamin B12 inhibits the maturation and division of cell nuclei, leading to anemia.

Uso

Administer subcutaneously or intramuscularly:

Calves, buffalo calves: Inject 4–8 ml per animal subcutaneously during the first week of life.
Piglets: Inject 1 ml per piglet intramuscularly at 3 days of age.

WITHDRAWAL PERIOD: Not required.

Recomendaciones

DRUG INTERACTIONS:
Do not use concurrently with other oral iron supplements.

USE DURING PREGNANCY:
High doses increase the risk of teratogenicity and fetal toxicity.

Contraindicaciones

Do not use in animals with kidney infections.

Do not use simultaneously with tetracyclines due to interactions between iron and tetracyclines.

Efectos secundarios

In pigs, iron injections may occasionally cause reactions such as exhaustion, muscle weakness, vomiting, fever, and abscesses at the injection site. Rarely, hypersensitivity reactions or sudden death may occur after injection.

Fecha de caducidad

2 years from the manufacturing date.

Almacenamiento

Store in a cool, dry place at temperatures below 30°C. Avoid direct sunlight.

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información adicional

Ingrediente

Each 1 ml of solution contains:

Iron dextran ................. 100 mg
Vitamin B12 .................. 100 mcg
Solvent q.s. ..................... 1 ml

Uses

Prevention and treatment of anemia in calves, buffalo calves, and piglets.

Propiedades farmacológicas

Iron dextran is a complex of Fe(OH)₃ and dextran with a molecular weight of 5,000–7,500. Iron is essential in treating anemia, and iron deficiency is a major cause of anemia.

After intramuscular injection, the drug is absorbed via the lymphatic system: about 60% of the dose is absorbed within 3 days, and 90% within 1–3 weeks. Most absorption and transport of dextran iron from the injection site to the lymphatic system are handled by macrophages. Some dextran iron may remain around the connective tissues near the injection site and is absorbed slowly over several months.
Once absorbed, dextran iron rapidly enters the bloodstream via the lymphatic system and is gradually taken up by cells in the reticuloendothelial system (liver, spleen, bone marrow). Iron is released from the dextran complex, and dextran is either metabolized or excreted. Iron immediately binds to proteins such as hemosiderin, transferrin, or ferritin. Iron can cross the placenta, though the exact form is unknown. Only a small amount is excreted through milk.
Iron is not completely eliminated from the body. Free iron from hemoglobin breakdown is reused by the body, with only small amounts lost through hair and nail growth, skin shedding, and gastrointestinal mucosal turnover. Iron accumulation can occur with repeated doses, with minimal excretion via feces, bile, or urine.

Vitamin B12 is crucial for DNA synthesis. A deficiency in Vitamin B12 inhibits the maturation and division of cell nuclei, leading to anemia.

Uso

Administer subcutaneously or intramuscularly:

Calves, buffalo calves: Inject 4–8 ml per animal subcutaneously during the first week of life.
Piglets: Inject 1 ml per piglet intramuscularly at 3 days of age.

WITHDRAWAL PERIOD: Not required.

Recomendaciones

DRUG INTERACTIONS:
Do not use concurrently with other oral iron supplements.

USE DURING PREGNANCY:
High doses increase the risk of teratogenicity and fetal toxicity.

Contraindicaciones

Do not use in animals with kidney infections.

Do not use simultaneously with tetracyclines due to interactions between iron and tetracyclines.

Efectos secundarios

Fecha de caducidad

2 years from the manufacturing date.

Almacenamiento

Store in a cool, dry place at temperatures below 30°C. Avoid direct sunlight.

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PRODUCTOS RELACIONADOS

Aa-Vicom

Provides a source of amino acids and vitamins.

ADE Fort

ADE FORT is intended for use as an aid in the prevention and treatment of vitamin A, D and E deficiencies in pigs, sheep and cattle.

Astryl

Treatment of respiratory and digestive tract infections, typhoid in buffalo, cows, pigs and poultry

ATP 3+

Supports energy metabolism for organs like the heart, muscles, liver, and immune cells.

B12 3+

A vital component for cellular activities.

B12-ATP

Anti-fatigue – Health recovery – Stress prevention

Bcom ADE

Treatment for growth disorders, reduced appetite, poor feeding.

Butal-AD

A component of ATP—the energy source for muscle and bone cells.

Calbiron

Treatment for calcium deficiency and anemia.

Calci-B6

For deficiencies in calcium, magnesium, methionine, lysine, and vitamins.

CEFQUINO-DC

Fourth-generation Cephalosporin.Effective against multiple pathogens

Chymosin

Biological anti-inflammatory preparation.Breaks down casein and fibrin in infectious diseases

Chymosin-XL

Biological anti-inflammatory product

Dexmin

Combination of glucocorticoid and antihistamine

Diclodol

Pain relief - Fever reduction - Anti-inflammatory

Doxy-Sone

Dual Antibiotics – Rapid Absorption – Wide Distribution

Doxysone LA

Dual-action antibiotic with a 48-hour prolonged effect.Fast absorption – wide distribution.

Florcol-LA

Specialized for respiratory and gastrointestinal diseases

Flortyl-LA

Effective against Gram-negative and Gram-positive bacteria

Fluroquin

Antibiotics are widely used in veterinary medicine to treat diseases in cattle, pigs and poultry.

Fosfocin

Treatment of coryza, pasteurellosis,bronchopneumonia, mastitis, genital tract infections.

Loximol

The alleviation of inflammation and pain in both acute and chronic musculo-skeletal disorders.

Marbo-10

Effective against pneumonia and MMA (Mastitis-Metritis-Agalactia).

Mectin

Causes paralysis of worms, immobilizes, and eliminates larvae through the lymphatic system.

Nutrisal

Acts as a reserve energy source (ATP) for muscle and bone cells.

Rimaco FA

Effective against both Gram(-) and Gram (+) bacteria.

Spec-Lin

For the treatment of infections caused by bacteria sensitive to Lincomycin and Spectinomycin.

Tylan-100

Special treatment for asthma, pneumonia, acute and chronic respiratory tract infections.

Vita Bcomplex

Promotes absorption and metabolism in animals, especially animals with metabolic disorders and weak resistance.

ZUTIDYL-LP

Rapid absorption and effective distribution to lung tissues and infection sites.

Zutidyl-XL

Has a special bactericidal effect because the drug reaches high concentrations in plasma.

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