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Calbiron

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Treatment for calcium deficiency and anemia.

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Calbiron Calbiron
Ingredient

Each 1 ml solution contains:

  • Calcium Gluconate .......... 200 mg
  • Cyanocobalamin (Vitamin B12) .......... 0.4 mg
  • Solvent (qs) .......... 1 ml
Uses

For the treatment of:

  • Calcium deficiency and hypocalcemia-induced paralysis after childbirth and during lactation.
  • Weakness, rickets, osteomalacia, and stunted growth in young animals.
  • Vascular protection, prevention of bleeding, hemorrhage, and edema in cattle, buffalo, horses, pigs, goats, sheep, dogs, cats, and poultry.

USE DURING PREGNANCY AND LACTATION:

Safe for use.

Pharmacological properties

Calcium Gluconate: A calcium supplement. After administration, the calcium ion excreted in urine is the difference between the amount filtered by the glomeruli and the amount reabsorbed. Tubular reabsorption is highly effective, with over 98% of calcium ions filtered by the glomeruli being reabsorbed into the bloodstream. Reabsorption efficiency is primarily regulated by parathyroid hormone and is influenced by sodium clearance, the presence of non-reabsorbable anions, and diuretics. Significant amounts of calcium are excreted in milk during lactation, and small amounts are also eliminated through sweat and feces.

Vitamin B12 (Cyanocobalamin): Essential for DNA synthesis. Vitamin B12 deficiency inhibits nuclear cell division and maturation, leading to anemia.

Usage

Administer intramuscularly, intravenously, or subcutaneously.

  • For rickets and anemia:
  • For paralysis:
  • For hemorrhage prevention:

WITHDRAWAL PERIOD:

Not required.

Recommendations

Drugs that inhibit calcium excretion: Ciprofloxacin, thiazides, and anticonvulsants.

Calcium absorption interference: Calcium reduces the absorption of doxycycline, oxytetracycline, norfloxacin, enrofloxacin, and minerals like iron and zinc.

Drugs lowering blood calcium: Furosemide and estrogen.

Vitamin B12 interactions: Chloramphenicol reduces its hematopoietic response, Vitamin C inactivates Vitamin B12, and drugs like omeprazole, colchicine, neomycin, extended-release potassium compounds, and aminosalicylic acid may decrease Vitamin B12 absorption.

INCOMPATIBILITIES:

Calcium gluconate precipitates with carbonate, bicarbonate, phosphate, sulfate, and tartrate.

Side effects
  • Constipation
  • Nausea
  • Rash
  • Pain or a warm sensation (due to calcium gluconate)
Expiry date

2 years from the manufacturing date.

Storage

Store in a cool, dry place below 30°C, away from direct sunlight.

Additional Information
Ingredient

Each 1 ml solution contains:

  • Calcium Gluconate .......... 200 mg
  • Cyanocobalamin (Vitamin B12) .......... 0.4 mg
  • Solvent (qs) .......... 1 ml
Uses

For the treatment of:

  • Calcium deficiency and hypocalcemia-induced paralysis after childbirth and during lactation.
  • Weakness, rickets, osteomalacia, and stunted growth in young animals.
  • Vascular protection, prevention of bleeding, hemorrhage, and edema in cattle, buffalo, horses, pigs, goats, sheep, dogs, cats, and poultry.

USE DURING PREGNANCY AND LACTATION:

Safe for use.

Pharmacological properties

Calcium Gluconate: A calcium supplement. After administration, the calcium ion excreted in urine is the difference between the amount filtered by the glomeruli and the amount reabsorbed. Tubular reabsorption is highly effective, with over 98% of calcium ions filtered by the glomeruli being reabsorbed into the bloodstream. Reabsorption efficiency is primarily regulated by parathyroid hormone and is influenced by sodium clearance, the presence of non-reabsorbable anions, and diuretics. Significant amounts of calcium are excreted in milk during lactation, and small amounts are also eliminated through sweat and feces.

Vitamin B12 (Cyanocobalamin): Essential for DNA synthesis. Vitamin B12 deficiency inhibits nuclear cell division and maturation, leading to anemia.

Usage

Administer intramuscularly, intravenously, or subcutaneously.

  • For rickets and anemia:
  • For paralysis:
  • For hemorrhage prevention:

WITHDRAWAL PERIOD:

Not required.

Recommendations

Drugs that inhibit calcium excretion: Ciprofloxacin, thiazides, and anticonvulsants.

Calcium absorption interference: Calcium reduces the absorption of doxycycline, oxytetracycline, norfloxacin, enrofloxacin, and minerals like iron and zinc.

Drugs lowering blood calcium: Furosemide and estrogen.

Vitamin B12 interactions: Chloramphenicol reduces its hematopoietic response, Vitamin C inactivates Vitamin B12, and drugs like omeprazole, colchicine, neomycin, extended-release potassium compounds, and aminosalicylic acid may decrease Vitamin B12 absorption.

INCOMPATIBILITIES:

Calcium gluconate precipitates with carbonate, bicarbonate, phosphate, sulfate, and tartrate.

Side effects
  • Constipation
  • Nausea
  • Rash
  • Pain or a warm sensation (due to calcium gluconate)
Expiry date

2 years from the manufacturing date.

Storage

Store in a cool, dry place below 30°C, away from direct sunlight.

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RELATED PRODUCTS

Aa-Vicom

Aa-Vicom

Provides a source of amino acids and vitamins.

ADE Fort

ADE Fort

ADE FORT is intended for use as an aid in the prevention and treatment of vitamin A, D and E deficiencies in pigs, sheep and cattle.

Astryl

Astryl

Treatment of respiratory and digestive tract infections, typhoid in buffalo, cows, pigs and poultry

ATP 3+

ATP 3+

Supports energy metabolism for organs like the heart, muscles, liver, and immune cells.

B12 3+

B12 3+

A vital component for cellular activities.

B12-ATP

B12-ATP

Anti-fatigue – Health recovery – Stress prevention

Bcom ADE

Bcom ADE

Treatment for growth disorders, reduced appetite, poor feeding.

Butal-AD

Butal-AD

A component of ATP—the energy source for muscle and bone cells.

Calci-B6

Calci-B6

For deficiencies in calcium, magnesium, methionine, lysine, and vitamins.

CEFQUINO-DC

CEFQUINO-DC

Fourth-generation Cephalosporin.Effective against multiple pathogens

Chymosin

Chymosin

Biological anti-inflammatory preparation.Breaks down casein and fibrin in infectious diseases

Chymosin-XL

Chymosin-XL

Biological anti-inflammatory product

Dexmin

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Combination of glucocorticoid and antihistamine

Diclodol

Diclodol

Pain relief - Fever reduction - Anti-inflammatory

Doxy-Sone

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Dual Antibiotics – Rapid Absorption – Wide Distribution

Doxysone LA

Doxysone LA

Dual-action antibiotic with a 48-hour prolonged effect.Fast absorption – wide distribution.

Fe-B12

Fe-B12

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Florcol-LA

Florcol-LA

Specialized for respiratory and gastrointestinal diseases

Flortyl-LA

Flortyl-LA

Effective against Gram-negative and Gram-positive bacteria

Fluroquin

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Antibiotics are widely used in veterinary medicine to treat diseases in cattle, pigs and poultry.

Fosfocin

Fosfocin

Treatment of coryza, pasteurellosis,bronchopneumonia, mastitis, genital tract infections.

Loximol

Loximol

The alleviation of inflammation and pain in both acute and chronic musculo-skeletal disorders.

Marbo-10

Marbo-10

Effective against pneumonia and MMA (Mastitis-Metritis-Agalactia).

Mectin

Mectin

Causes paralysis of worms, immobilizes, and eliminates larvae through the lymphatic system.

Nutrisal

Nutrisal

Acts as a reserve energy source (ATP) for muscle and bone cells.

Rimaco FA

Rimaco FA

Effective against both Gram(-) and Gram (+) bacteria.

Spec-Lin

Spec-Lin

For the treatment of infections caused by bacteria sensitive to Lincomycin and Spectinomycin.

Tylan-100

Tylan-100

Special treatment for asthma, pneumonia, acute and chronic respiratory tract infections.

Vita Bcomplex

Vita Bcomplex

Promotes absorption and metabolism in animals, especially animals with metabolic disorders and weak resistance.

ZUTIDYL-LP

ZUTIDYL-LP

Rapid absorption and effective distribution to lung tissues and infection sites.

Zutidyl-XL

Zutidyl-XL

Has a special bactericidal effect because the drug reaches high concentrations in plasma.

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